Bed and breakfast, 4-star201 North Main Street, Hannibal, MO, United StatesShow on map
Guests rate it highest for location, cleanliness and service.
9.0205ReviewsRiverside Retreat with Spa Bath
Historic Charm: Nestled in a historic building, Main Street Bed & Breakfast offers a unique stay with views of the river. The property boasts barbecue facilities for guests to enjoy.
Luxurious Amenities: Guests can indulge in a spa bath and relax in the hot tub during their stay. The accommodation also features air conditioning, flat-screen TVs with streaming services, and complimentary WiFi.
Explore and Unwind: Perfect for outdoor enthusiasts, the B&B offers activities like cycling, fishing, and hiking in the picturesque surroundings of Hannibal. After a day of adventures, unwind with a walking tour or pub crawl nearby.
9.0
Rated 9.0 out of 10 by 205 guests who stayed here.
Perfect location!
Convenient location
The spiral staircase was scarry, especially at night with poor lighting.
Location was good. Bed is very comfortable. Host was hospitable.
Too much light comes in the very large windows. Over night there are street lights right outside coming in full blast. I would recommend black outs for…
Location, room and host are superb.
N/A
The fresh bread was great. The room was very clean and comfortable. We loved the design.
That’s hard to say.Everything was great.
The bathroom and location were great. The building is authentic and room looks nice.
The breakfast is not as expected. No fresh breakfast and no breakfast room. Price does not justify what you get. The building is quite…
Reviews are written by guests who booked through our supplier and stayed, shown as written and in their own language. Category scores are the supplier’s reading of recent reviews, updated January 2026.
201 North Main Street, Hannibal, MO, United States
Guests rate the location 9.8 out of 10 — exceptional.
Each room shows its own terms before you pay.
Most rates can be cancelled free until a date shown on the room.
Non-refundable rates are marked as such.
Check-in from 2:00 PM until 08:00 PM
Check-out by 11:00 AM
Children welcome
No pets
Free parking on site
Non-smoking rooms available
Paid when you book, not at the desk.
Rates include the taxes and fees we can read.
The property may take a card at check-in for incidentals.
Street parking is available on site. Please note that breakfast consists of muffins, fresh fruit, granola bars, yogurt, and fruit juice for two. The coffee machine is equipped with Columbian coffee, decaf, and tea. Chips, candy, and bottled water are also provided. Food and beverages are provided in the room before check-in. Hot breakfast is not available.Guests are required to show a photo ID and credit card upon check-in. Please note that all Special Requests are subject to availability and additional charges may apply. Please inform of your expected arrival time in advance. You can use the Special Requests box when booking, or contact the property directly using the contact details in your confirmation. This property does not accommodate bachelor(ette) or similar parties. A deposit may be required at the property.
Check-in is from 2:00 PM. Check-out is by 11:00 AM. If you're arriving late, tell us and we'll ask the property to hold the room.
No — the property states that pets are not allowed.
Yes — the property states that parking on site is free. Whether a space can be reserved in advance varies, so we check it against your dates.
Breakfast is offered at the property. Whether it's included depends on the rate — the board type is shown on each room once you put your dates in.
Yes — internet access is listed among the property's facilities.
Put your dates in above and book online, or call (888) 789-8585 and we'll do it for you — including things a booking form can't handle, like a block of rooms, a monthly rate or an invoice for your employer.
201 North Main Street, Hannibal, MO.
Nothing to do with the booking above. The same market, priced the same way, for if this one is not it.