Fabulous
Guests rate it highest for service, location and rooms.
8.91,122Reviews- Check-in from 3:00 PMCheck-out by 12:00 PM. The front desk is staffed around the clock, so a late arrival is fine.
- Superb locationGuests rate the location 9.4 out of 10, at Alonso 26.
Central Location and Charming Accommodation Hotel Santa Regina offers a charming stay in the heart of Guanajuato, just steps away from Jardín de la Unión Gardens and Guanajuato University.
Comfortable Rooms with Modern Amenities Each spacious room at Santa Regina Hotel is elegantly decorated and equipped with a flat-screen TV, fan, and free Wi-Fi, ensuring a comfortable stay for guests.
Convenient Services and Nearby Attractions Enjoy a complimentary breakfast at a nearby hotel, explore the variety of dining options in the area, and visit popular attractions like Juarez Theatre and Pípila Monument within walking distance.
Ready to experience the charm of Hotel Santa Regina? Book your stay now for an unforgettable visit to Guanajuato!
What this place offers
- WiFi available
- Free WiFi
- Non-smoking rooms
- 24-hour front desk
- Family rooms
- Lift / Elevator
- Laundry
- Luggage storage
- Tour desk
- Ironing service
Rooms
8.9
Fabulous
Rated 8.9 out of 10 by 1,122 guests who stayed here.
- Cleanliness8.4
- Service9.4
- Location9.4
- Rooms8.9
- Amenities8.4
- Value8.9
- Food & drink8.4
Guests mention
Central locationFriendly staffClean rooms
PamelaMexicoTodo excelente!!
Incluye bufet pero sii deja mucho que decir no esta a la altura de la exelencia del hotel
Lidia GabrielaMexicoLa ubicación fantástica, y el elevador
El ve ntilador del techo, queda muy separado de la cama
DANN ALVAREZMexicoHotel Santa Regina excelente opción para alojarse en Guanajuato
Me encantó el trato del personal y la habitación tan amplia, cómoda y limpia. Sin duda volveré a Guanajuato y Hotel Santa Regina será mi opción de hospedaje.
Que el restaurante para el desayuno sea en otro hotel, las…
Maria Esther VazquezArgentinaLo recomiendo
La ubicacion, el personal,la higiene.
No hubo nada que no nos gustara.
Bessy LissethSVFue maravillosa la estancia, en relación ubicación , lugar, limpieza y personal 100% los felicito
Excelente y limpio 100% recomendado
No tengo quejas todo EXCELENTE
aguilarMexicoLas habitaciones cómodas, me agrado el desayuno tipo Buffet. El personal es muy amable.
Reviews are written by guests who booked through our supplier and stayed, shown as written and in their own language. Category scores are the supplier’s reading of recent reviews, updated January 2026.
Where you’ll be
Alonso 26, Guanajuato, Mexico
Guests rate the location 9.4 out of 10 — superb.
Things to know
Cancellation
Each room shows its own terms before you pay.
Most rates can be cancelled free until a date shown on the room.
Non-refundable rates are marked as such.
House rules
Check-in from 3:00 PM
Check-out by 12:00 PM
Children welcome
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No pets
Non-smoking rooms available
Payment & property
Paid when you book, not at the desk.
Rates include the taxes and fees we can read.
The property may take a card at check-in for incidentals.
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Breakfast is also served at La Casona de Don Lucas.Guests are required to show a photo ID and credit card upon check-in. Please note that all Special Requests are subject to availability and additional charges may apply. A deposit may be required at the property.
What we’d check for you here
- That the desk is staffed when you land, and that the room is held past cut-off.
- Whether the rate moves for your dates, and what it includes.
- What the property actually charges at the desk on top of the rate.
Questions about Hotel Santa Regina
What time is check-in and check-out at Hotel Santa Regina?
Check-in is from 3:00 PM. Check-out is by 12:00 PM. If you're arriving late, tell us and we'll ask the property to hold the room.
Does Hotel Santa Regina allow pets?
No — the property states that pets are not allowed.
Does Hotel Santa Regina have Wi-Fi?
Yes — internet access is listed among the property's facilities.
Can I check in late at Hotel Santa Regina?
The property lists a front desk staffed 24 hours, so a late arrival should be possible. Standard check-in is from 3:00 PM. Rooms are still released after a cut-off at some properties regardless of the desk hours, so tell us your arrival time and we'll have them hold it.
How do I book Hotel Santa Regina?
Put your dates in above and book online, or call (888) 789-8585 and we'll do it for you — including things a booking form can't handle, like a block of rooms, a monthly rate or an invoice for your employer.
Where is Hotel Santa Regina?
Alonso 26, Guanajuato.
Other places we book in Guanajuato
Nothing to do with the booking above. The same market, priced the same way, for if this one is not it.
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