Best Western Santa Fe
Hotel, 3-star4600 Interstate 40 East, Amarillo, TX, United StatesShow on map
Fabulous
Guests rate it highest for service, location and food.
8.7800Reviews- Check-in from 3:00 PMCheck-out by 11:00 AM. The front desk is staffed around the clock, so a late arrival is fine.
- Superb locationGuests rate the location 9.0 out of 10, at 4600 Interstate 40 East.
- Free parkingThe property states parking on site is free for guests.
Convenient Location Less than 15 minutes from the airport, Best Western Santa Fe Inn offers easy access to attractions like the American Quarter Horse Hall of Fame & Museum and Wonderland Amusement Park.
Comfortable Accommodations Each room is equipped with essential amenities such as a refrigerator, microwave, and free WiFi, ensuring a cozy stay. Enjoy cable TV and a spacious work area in every room.
Relaxing Amenities Take a refreshing dip in the outdoor pool or stay active with complimentary passes to a nearby fitness center. Start your day right with a full hot breakfast and make use of the on-site business center.
Book your stay at Best Western Santa Fe Inn now to experience convenience, comfort, and relaxation all in one place.
What this place offers
- WiFi available
- Parking
- Free Parking
- Non-smoking rooms
- Air conditioning
- Swimming pool
- 24-hour front desk
- Business center
- Heating
- Pets allowed
Rooms
8.7
Fabulous
Rated 8.7 out of 10 by 800 guests who stayed here.
- Cleanliness8.2
- Service9.0
- Location9.0
- Rooms8.5
- Amenities8.5
- Value8.7
- Food & drink9.0
Guests mention
Clean roomsFriendly staffGreat breakfast
AliUnited StatesScary place to stay! Not safe!
It was easy to get a last minute room along the interstate.
Scary place to stay! We arrived (mom and daughter) at 11:30 pm. Check in was easy. But then walking to our room became weird. Several rooms had their doors…
DENISEUnited StatesBreakfast was not very good
RoopaUnited StatesEfficient location for a one night stay.
Pet friendly hotel with decent furnishings, hot coffee in the lobby and quick check-in process.
Though they say pet friendly, pets are not allowed in the breakfast area. So I could not avail breakfast services.
JimUnited StatesAbsolutely awful
Nothing
Almost everything
AlvinUnited StatesWe were glad they were pet friendly and place was clean.
Easy access, pet friendly
ALEKSONCanadaReally good
The brunch and staff taking care of the brunch
Reviews are written by guests who booked through our supplier and stayed, shown as written and in their own language. Category scores are the supplier’s reading of recent reviews, updated January 2026.
Where you’ll be
4600 Interstate 40 East, Amarillo, TX, United States
Guests rate the location 9.0 out of 10 — superb.
Things to know
Cancellation
Each room shows its own terms before you pay.
Most rates can be cancelled free until a date shown on the room.
Non-refundable rates are marked as such.
House rules
Check-in from 3:00 PM
Check-out by 11:00 AM
Children welcome
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No pets
Free parking on site
Non-smoking rooms available
Payment & property
Paid when you book, not at the desk.
Rates include the taxes and fees we can read.
The property may take a card at check-in for incidentals.
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Guests are required to show a photo ID and credit card upon check-in. Please note that all Special Requests are subject to availability and additional charges may apply. Guests under the age of 18 can only check in with a parent or official guardian. A deposit may be required at the property.
What we’d check for you here
- That the step-free room is actually free on your dates, and whether it is a roll-in shower or a bath, which the listing never says.
- That the desk is staffed when you land, and that the room is held past cut-off.
- The pet fee and any size limit, which is where these bookings usually come apart.
- Whether there is room for a pickup, a trailer or a van, not just a car.
- Whether the rate moves for your dates, and what it includes.
- What the property actually charges at the desk on top of the rate.
Questions about Best Western Santa Fe
What time is check-in and check-out at Best Western Santa Fe?
Check-in is from 3:00 PM. Check-out is by 11:00 AM. If you're arriving late, tell us and we'll ask the property to hold the room.
Does Best Western Santa Fe allow pets?
No — the property states that pets are not allowed.
Is there parking at Best Western Santa Fe?
Yes — the property states that parking on site is free. Whether a space can be reserved in advance varies, so we check it against your dates.
Does Best Western Santa Fe have a pool?
Yes — a pool is listed among the property's facilities. Seasonal closures are common, so we'll confirm it's open for your dates.
Does Best Western Santa Fe have Wi-Fi?
Yes — internet access is listed among the property's facilities.
Does Best Western Santa Fe have wheelchair accessible rooms?
The property lists step-free or accessible facilities. That flag is the one least able to settle the question: a hotel can carry it and still have a step at the entrance, or a bath rather than a roll-in shower, and it does not say whether the accessible room is free on your dates. Tell us what you need and we'll ask the property directly rather than reading you the flag.
Can I check in late at Best Western Santa Fe?
The property lists a front desk staffed 24 hours, so a late arrival should be possible. Standard check-in is from 3:00 PM. Rooms are still released after a cut-off at some properties regardless of the desk hours, so tell us your arrival time and we'll have them hold it.
How do I book Best Western Santa Fe?
Put your dates in above and book online, or call (888) 789-8585 and we'll do it for you — including things a booking form can't handle, like a block of rooms, a monthly rate or an invoice for your employer.
Where is Best Western Santa Fe?
4600 Interstate 40 East, Amarillo, TX.
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